Histopathological studies on the curative role of Mentha longifolia in Trypanosoma evansi experimentally infected rats
نویسندگان
چکیده
Trypanosomiasis is an important protozoan disease of domestic animals and man. One the pathogenic trypanosomes in Trypanosoma evansi; causative agent Surra that highly fatal to a number domesticated mammals such as camels. Mentha longifolia plant has been used traditional medicine treat some parasitic microbial diseases different countries. This study was conducted evaluate antitrypanosomal activity leaf ethanolic extract M. against experimentally induced T. evansi infection rats. A total 16 male albino rats were allocated into four groups each; uninfected control group (CG), (PG), trypanosome infected (TG), infected treated (plant + trypanosome) (PTG). Blood tissue samples collected from on 35th day after treatment. Hematological results obtained evansi-infected showed microcytic hypochromic anemia with significance (P< 0.05). There significant 0.05) increase leukocytic count (TLC) neutrophils, eosinophils, monocytes TG) compared those CG, PG, PTG. Histopathological examination revealed necrosis, hydropic degeneration liver apoptosis, hemorrhage, edema, inflammatory cell infiltration kidney, demyelination brain, lymphocytic granuloma lung. Results present not effective vivo, despite its high vitro.
منابع مشابه
Evaluation of Humoral Immune Response to Foot-and-Mouth Disease Vaccination in Experimentally Infected Guinea Pigs with Trypanosoma evansi
متن کامل
A Preliminary Comparative Study on the Efficacy of Quinapyramine Sulphate/chloride and Melarsoprol in Rats, Experimentally Infected with Trypanosoma Evansi
Using standard parasitological, pathological, haematological and sero-biochemical methods, the trypanocidal effect of quinapyramine sulphate/chloride and melarsoprol has been compared in rats experimentally infected with Trypanosoma evansi isolated from a camel. The results indicated that infection in all rats resulted in fulminating parasitaemia (> 10 trypanosomes per mL). One week after treat...
متن کاملthe effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولHaematological changes in Trypanosoma evansi infected cattle
During the three years period of study twelve cross bred cattle were identified that they were suffering with clinical Trypanosomiasis. Up on clinical examination cattle had anorexia, fever, ocular discharges, dullness and enlarged lymph nodes. Stained peripheral blood examination revealed the presence of Trypanosoma evansi. Haematological abnormalities include decreased TEC, PCV, Hb and TLC va...
متن کاملExpression of regulatory dendritic cell-related cytokines in cattle experimentally infected with Trypanosoma evansi
Trypanosoma evansi causes wasting disease in many livestock. T. evansi infection gives rise to inflammatory immune responses, which contribute to the development of inflammation-associated tissue injury. We previously reported that regulatory dendritic cells (DCs), which act as potential regulators of inflammation, were activated in infected mice and transfer of regulatory DCs to infected mice ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Veterinary Medical Research
سال: 2021
ISSN: ['2357-0520', '2357-0512']
DOI: https://doi.org/10.21608/jvmr.2021.61380.1033